Genetic Research Pinpoints a Lethal Risk Linked to Adams-Oliver Syndrome
Disrupted heart and vascular development traced to gene variants affecting NOTCH1 signaling Scientists at Cincinnati Children's have taken a key early step in understanding why some people born with the rare disease Adams-Oliver syndrome (AOS) experience potentially fatal disruptions in heart and vascular development. https://mma.prnewswire.com/media/2835580/Cincinnati_Childrens_Hospital_Medical_Center_AOS.jpg The study, published Dec. 1, 2025, in JCI, reports developing […]