Sobi Q3 2025 report: Accelerated growth and portfolio momentum

Swedish Orphan Biovitrum AB (publ) (Sobi®) today announced its report for the third quarter 2025

Third Quarter 2025

— Total revenue increased 13 per cent, 21 per cent at constant exchange rates, (CER)1, to SEK 7,776 M (6,894)

— Haematology revenue increased 26 per cent at CER to SEK 4,771 M (4,000), mainly driven by Altuvoct of SEK 769 M (129), strong sales of Doptelet of SEK 1,408 M (1,039) and sales of Aspaveli/Empaveli of SEK 317 M (270), somewhat offset by low Vonjo sales of SEK 307 M (379)

— Immunology revenue increased 12 per cent at CER to SEK 2,658 M (2,583), driven by strong sales of Gamifant of SEK 733 M (405) and Kineret sales of SEK 769 M (699), somewhat offset by lower Beyfortus royalty of SEK 1,166 M (1,478)

— Revenue from the strategic portfolio1* grew by 39 per cent at CER to SEK 5,001 M (3,830)

— The product and marketing right Vonjo was impaired by SEK 6,612 M before tax. The impairment has not affected cash flow and is reported as items affecting comparability (IAC2)

— The adjusted EBITA margin1,2 was 47 per cent (43), excluding IAC2 of SEK -6,664 M. EBITA1 was SEK 3,620 M (2,923), corresponding to a margin of 47 per cent (42). EBIT was SEK -3,858 M (2,038) including the impairment of Vonjo by SEK 6,612 M

— Earnings per share (EPS) before dilution was SEK -8.40 (4.27) and EPS after dilution was SEK -8.32 (4.22). Adjusted EPS before dilution1 was SEK 6.11 (4.36) and adjusted EPS after dilution1 was SEK 6.05 (4.31). Cash flow from operating activities was SEK 1,840 M (1,201)

Outlook 2025 – updated

— Revenue is anticipated to grow at low double-digit percentage at CER (previously high-single-digit)

— Adjusted EBITA margin adjusted is anticipated to be at mid-to-high 30s percentage of revenue (previously mid-30s)

Financial summary

SEK M Q3 Q3 Change Jan-Sep Jan-Sep Change FY 2025 2024 2025 2024 2024Total revenue 7,776 6,894 13% 20,417 18,592 10% 26,027Gross profit 6,162 5,563 11% 15,788 14,407 10% 20,242Gross margin1 79% 81% 77% 77% 78%Adjusted gross margin1,2 80% 81% 78% 78% 78%EBITA1 3,620 2,923 24% 7,743 6,585 18% 9,158Adjusted EBITA1,2 3,672 2,965 24% 8,124 6,811 19% 9,368EBITA margin1 47% 42% 38% 35% 35%Adjusted EBITA margin1,2 47% 43% 40% 37% 36%Profit/loss for the period -2,895 1,464 >-200% -1,386 2,488 -156% 3,879EPS before dilution, SEK -8.40 4.27 >-200% -4.02 7.29 -155% 11.37Adjusted EPS before dilution, SEK1,2 6.11 4.36 40% 11.25 7.80 44% 11.83EPS after dilution, SEK -8.32 4.22 >-200% -3.99 7.21 -155% 11.24Adjusted EPS after dilution, SEK1,2 6.05 4.31 40% 11.14 7.71 45% 11.69

— Alternative Performance Measures (APMs)

— Items affecting comparability (IAC)

* The strategic portfolio includes Sobi's medicines Altuvoct, Aspaveli/Empaveli, Doptelet, Gamifant, Vonjo and Zynlonta, and royalty on Sanofi's sales of Altuviiio and Beyfortus.

Investors, analysts, and the media are invited to a conference call on the same day at 13:00 CEST, 12:00 BST, and 07:00 EDT. The call will include a presentation of the results and a Q&A session.

The presentation can be followed live hereor afterwards on sobi.com. The slides will be made available on sobi.com before the conference call.

To participate in the conference call, please use the following dial-in details: Sweden: +46 8 5051 0031 United Kingdom: +44 207 107 06 13 United States: +1 631 570 56 13

For other countries, please find the details here.

For details on how to contact theSobi Investor Relations Team, please click here. For Sobi Media contacts, click here.

This information is information that Sobi is obliged to make public pursuant to the EU Market Abuse Regulation. The information was submitted for publication, through the agency of the contact person set out below, at 08:00CEST on 20October 2025.

Gerard Tobin Head of Investor Relations

This information was brought to you by Cision http://news.cision.com.

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SOURCE Swedish Orphan Biovitrum AB

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