Avantor® Reports Second Quarter 2025 Results

— Net sales of $1.68 billion, decrease of 1%; organic revenue was flat

— Net income of $65 million; Adjusted EBITDA of $280 million

— Diluted GAAP EPS of $0.09; adjusted EPS of $0.24

— Operating cash flow of $154 million; free cash flow of $125 million

Avantor, Inc. (NYSE: AVTR), a leading global provider of mission-critical products and services to customers in the life sciences and advanced technology industries, today reported financial results for its second fiscal quarter ended June 30, 2025.

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“In the second quarter, we remained focused on driving growth, enhancing operating leverage, and executing with discipline,” said Michael Stubblefield, President and Chief Executive Officer.

“Our Laboratory Solutions segment delivered sequential revenue growth in line with our expectations, as improvement initiatives began yielding tangible results. We also secured several major contract extensions with leading pharma companies, reinforcing our strong customer relationships and differentiated value proposition. In Bioscience Production, revenue also grew sequentially, though performance was impacted by planned maintenance as well as regulatory and commercial challenges at a few key accounts. We are actively executing mitigation plans and remain encouraged by the continued strength of our core monoclonal antibody platform.”

“Avantor's resilient business model, diversified portfolio, and long-standing customer relationships, coupled with our focus on operational excellence, position us to navigate near-term challenges and deliver long-term shareholder value,” Stubblefield concluded.

Second Quarter 2025

For the three months ended June 30, 2025, net sales were $1,683.4 million, a decrease of 1% compared to the second quarter of 2024. Foreign currency translation had a positive impact of 2% and M&A had a negative impact of 3%, resulting in flat sales on an organic basis.

Net income decreased to $64.7 million from $92.9 million in the second quarter of 2024, and adjusted net income was $161.2 million as compared to $168.0 million in the comparable prior period. Net income margin was 3.8%. Adjusted EBITDA was $279.8 million, and Adjusted EBITDA margin was 16.6%. Adjusted Operating Income was $252.2 million, and Adjusted Operating Income margin was 15.0%.

Diluted earnings per share on a GAAP basis was $0.09, while adjusted EPS was $0.24.

Operating cash flow was $154.4 million, while free cash flow was $125.4 million. Adjusted net leverage was 3.2x as of June 30, 2025.

Second Quarter 2025 – Segment Results

Laboratory Solutions

— Net sales were $1,122.1 million, a reported decrease of 3%, as compared to $1,155.7 million in the second quarter of 2024. Foreign currency translation had a positive impact of 2% and M&A had a negative impact of 4%, resulting in a 1% sales decline on an organic basis.

— Adjusted Operating Income was $133.3 million as compared to $150.9 million in the comparable prior period. Adjusted Operating Income margin was 11.9%.

Bioscience Production

— Net sales were $561.3 million, a reported increase of 3%, as compared to $547.1 million in the second quarter of 2024. Foreign currency translation had a positive impact of 1% resulting in a 2% sales increase on an organic basis.

— Adjusted Operating Income was $139.7 million as compared to $144.0 million in the comparable prior period. Adjusted Operating Income margin was 24.9%.

Adjusted Operating Income is Avantor's segment reporting profitability measure under generally accepted accounting principles and is used by management to measure and evaluate the performance of our Company's business segments.

CEO Transition As previously announced on July 21,Avantor has named life-sciences veteran Emmanuel Ligner as its next President and Chief Executive Officer, effective August 18, 2025. Mr. Ligner succeeds Michael Stubblefield, who will step down from his role as Director, President and Chief Executive Officer upon Mr. Ligner's appointment.

Conference Call We will host a conference call to discuss our results today, August 1, 2025, at 8:00 a.m. Eastern Time. The live webcast, presentation and supplemental disclosure package, as well as a replay, will be available on theinvestor section of Avantor's website.

About Avantor Avantor® is a leading life science tools company and global provider of mission-critical products and services to the life sciences and advanced technology industries. We work side-by-side with customers at every step of the scientific journey to enable breakthroughs in medicine, healthcare, and technology. Our portfolio is used in virtually every stage of the most important research, development and production activities at more than 300,000 customer locations in 180 countries. For more information, visitavantorsciences.comand find us onLinkedIn, X (Twitter) andFacebook.

Use of Non-GAAP Financial Measures To evaluate our performance, we monitor a number of key indicators. As appropriate, we supplement our results of operations determined in accordance with U.S. generally accepted accounting principles (“GAAP”) with certain non-GAAP financial measures that we believe are useful to investors, creditors and others in assessing our performance. These measures should not be considered in isolation or as a substitute for reported GAAP results because they may include or exclude certain items as compared to similar GAAP-based measures, and such measures may not be comparable to similarly titled measures reported by other companies. Rather, these measures should be considered as an additional way of viewing aspects of our operations that provide a more complete understanding of our business. We strongly encourage investors to review our consolidated financial statements included in reports filed with the SEC in their entirety and not rely solely on any one single financial measure or communication.

The non-GAAP financial measures used in this press release are sales growth (decline) on an organic basis, Adjusted Operating Income, Adjusted Operating Income margin, Adjusted EBITDA, Adjusted EBITDA margin, adjusted net income, adjusted EPS, adjusted net leverage, free cash flow and free cash flow conversion.

— Organic net sales growth (decline) eliminates from our reported net sales change the impacts of revenues from acquisitions and divestitures that occurred in the last year (as applicable) and changes in foreign currency exchange rates. We believe that this measurement is useful to investors as a way to measure and evaluate our underlying commercial operating performance consistently across our segments and the periods presented. This measure is used by our management for the same reason.

— Adjusted Operating Income is our net income or loss adjusted for the following items: (i) interest expense, (ii) income tax expense, (iii) amortization of acquired intangible assets, (iv) losses on extinguishment of debt, (v) charges associated with the impairment of certain assets, (vi) gain on sale of business, and (vii) certain other adjustments. Adjusted Operating Income margin is Adjusted Operating Income divided by net sales as determined under GAAP. We believe that these measures are useful to investors as ways to analyze the underlying trends in our business consistently across the periods presented. These measures are used by our management for the same reason. Additionally, Adjusted Operating Income is our segment reporting profitability measure under GAAP.

— Adjusted EBITDA is our net income or loss adjusted for the following items: (i) interest expense, (ii) income tax expense, (iii) amortization of acquired intangible assets, (iv) depreciation expense, (v) losses on extinguishment of debt, (vi) charges associated with the impairment of certain assets, (vii) gain on sale of business, and (viii) certain other adjustments. Adjusted EBITDA margin is Adjusted EBITDA divided by net sales as determined under GAAP. We believe that these measures are useful to investors as ways to analyze the underlying trends in our business consistently across the periods presented. These measures are used by our management for the same reason.

— Adjusted net income is our net income or loss first adjusted for the following items: (i) amortization of acquired intangible assets, (ii) losses on extinguishment of debt, (iii) charges associated with the impairment of certain assets, (iv) gain on sale of business, and (v) certain other adjustments. From this amount, we then add or subtract an assumed incremental income tax impact on the above-noted pre-tax adjustments, using estimated tax rates, to arrive at Adjusted Net Income. We believe that this measure is useful to investors as a way to analyze the business consistently across the periods presented. This measure is used by our management for the same reason.

— Adjusted EPS is our adjusted net income divided by our diluted GAAP weighted average share count adjusted for anti-dilutive instruments. We believe that this measure is useful to investors as an additional way to analyze the underlying trends in our business consistently across the periods presented. This measure is used by our management for the same reason.

— Adjusted net leverage is equal to our gross debt, reduced by our cash and cash equivalents, divided by our trailing 12-month Adjusted EBITDA (excluding stock-based compensation expense and including the expected run-rate effect of cost synergies and the incremental results of completed acquisitions and divestitures as if those acquisitions and divestitures had occurred on the first day of the trailing 12-month period). We believe that this measure is useful to investors as a way to evaluate and measure the Company's capital allocation strategies and the underlying trends in the business. This measure is used by our management for the same reason.

— Free cash flow is equal to our cash flows from operating activities, less capital expenditures, plus direct transaction costs and income taxes paid related to acquisitions and divestitures (as applicable) in the period. Free cash flow conversion is free cash flow divided by adjusted net income. We believe that these measures are useful to investors as they provide a view on the Company's ability to generate cash for use in financing or investing activities. These measures are used by our management for the same reason.

Reconciliations of these non-GAAP financial measures to the most directly comparable GAAP financial measures are included in the tables accompanying this release.

Forward-Looking and Cautionary Statements This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, and are subject to the safe harbor created thereby under the Private Securities Litigation Reform Act of 1995. All statements other than statements of historical fact included in this press release are forward-looking statements. Forward-looking statements discuss our current expectations and projections relating to our financial condition, results of operations, plans, including our cost transformation initiative, objectives, future performance and business. These statements may be preceded by, followed by or include the words “aim,” “anticipate,” “assumption,” “believe,” “continue,” “estimate,” “expect,” “forecast,” “goal,” “guidance,” “intend,” “likely,” “long-term,” “near-term,” “objective,” “opportunity,” “outlook,” “plan,” “potential,” “project,” “projection,” “prospects,” “seek,” “target,” “trend,” “can,” “could,” “may,” “should,” “would,” “will,” the negatives thereof and other words and terms of similar meaning.

Forward-looking statements are inherently subject to risks, uncertainties and assumptions; they are not guarantees of performance. You should not place undue reliance on these statements. We have based these forward-looking statements on our current expectations and projections about future events. Although we believe that our assumptions made in connection with the forward-looking statements are reasonable, we cannot assure you that the assumptions and expectations will prove to be correct. Factors that could contribute to these risks, uncertainties and assumptions include, but are not limited to, the factors described in “Risk Factors” in our most recent Annual Report on Form 10-K, and subsequent quarterly reports on Form 10-Q, as such risk factors may be updated from time to time in our periodic filings with the SEC.

All forward-looking statements attributable to us or persons acting on our behalf are expressly qualified in their entirety by the foregoing cautionary statements. In addition, all forward-looking statements speak only as of the date of this press release. We undertake no obligations to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise other than as required under the federal securities laws.

Investor Relations Contact Allison Hosak Senior Vice President, Global Communications Avantor 908-329-7281 Allison.Hosak@avantorsciences.com

Media Contact Eric VanZanten Head of External Communications Avantor 610-529-6219 Eric.Vanzanten@avantorsciences.com

Avantor, Inc. and subsidiariesUnaudited condensed consolidated statements of operations(in millions, except per share data) Threemonths ended Sixmonths ended June30, June30, 2025 2024 2025 2024Net sales $ 1,683.4 $ 1,702.8 $ 3,264.8 $ 3,382.6Cost of sales 1,129.3 1,121.3 2,175.8 2,230.6Gross profit 554.1 581.5 1,089.0 1,152.0Selling, general and administrative expenses 425.3 405.7 812.8 829.9Operating income 128.8 175.8 276.2 322.1Interest expense, net (43.4) (60.9) (85.6) (125.2)Loss on extinguishment of debt – (1.9) – (4.4)Other (expense) income, net (3.7) 1.6 (23.2) 2.7Income before income taxes 81.7 114.6 167.4 195.2Income tax expense (17.0) (21.7) (38.2) (41.9)Net income $ 64.7 $ 92.9 $ 129.2 $ 153.3Earnings per share:Basic $ 0.09 $ 0.14 $ 0.19 $ 0.23Diluted $ 0.09 $ 0.14 $ 0.19 $ 0.22Weighted average shares outstanding:Basic 681.5 679.4 681.3 678.7Diluted 681.8 682.6 682.0 681.9Avantor, Inc. and subsidiariesUnaudited condensed consolidated balance sheets(in millions) June 30, 2025 December 31, 2024AssetsCurrent assets:Cash and cash equivalents $ 449.4 $ 261.9Accounts receivable, net 1,149.4 1,034.5Inventory 779.8 731.5Other current assets 136.0 118.7Total current assets 2,514.6 2,146.6Property, plant and equipment, net 759.0 708.1Other intangible assets, net 3,350.2 3,360.2Goodwill, net 5,762.2 5,539.2Other assets 390.9 360.4Total assets $ 12,776.9 $ 12,114.5Liabilities and stockholders' equityCurrent liabilities:Current portion of debt $ 1,254.3 $ 821.1Accounts payable 708.8 662.8Employee-related liabilities 174.0 168.2Accrued interest 50.0 48.6Other current liabilities 388.6 306.8Total current liabilities 2,575.7 2,007.5Debt, net of current portion 2,988.2 3,234.7Deferred income tax liabilities 535.7 557.3Other liabilities 391.4 358.3Total liabilities 6,491.0 6,157.8Stockholders' equity:Common stock including paid-in capital 3,964.1 3,937.7Accumulated earnings 2,332.2 2,203.0Accumulated other comprehensive loss (10.4) (184.0)Total stockholders' equity 6,285.9 5,956.7Total liabilities and stockholders' equity $ 12,776.9 $ 12,114.5Avantor, Inc. and subsidiariesUnaudited condensed consolidated statements of cash flows(in millions) Threemonths ended Sixmonths ended June30, June30, 2025 2024 2025 2024Cash flows from operating activities:Net income $ 64.7 $ 92.9 $ 129.2 $ 153.3Reconciling adjustments:Depreciation and amortization 102.7 102.6 202.4 202.2Stock-based compensation expense 15.5 11.1 27.9 23.8Provision for accounts receivable and 14.9 15.5 26.9 39.5inventoryDeferred income tax benefit (17.6) (34.8) (30.0) (52.7)Amortization of deferred financing costs 2.3 2.8 4.5 5.8Loss on extinguishment of debt – 1.9 – 4.4Foreign currency remeasurement loss (gain) 1.9 (2.2) 3.8 3.1Pension termination charges – – 18.1 -Changes in assets and liabilities:Accounts receivable (12.5) (2.7) (55.7) -Inventory (15.7) (3.2) (33.3) (14.2)Accounts payable 10.9 89.5 19.1 45.9Accrued interest 10.7 9.2 1.4 (0.3)Other assets and liabilities (23.8) (2.9) (52.9) 6.4Other 0.4 1.4 2.3 5.5Net cash provided by operating activities 154.4 281.1 263.7 422.7Cash flows from investing activities:Capital expenditures (29.6) (45.8) (57.6) (80.5)Other 1.0 0.9 0.1 1.4Net cash used in investing activities (28.6) (44.9) (57.5) (79.1)Cash flows from financing activities:Debt borrowings – (28.9) – 12.3Debt repayments (6.8) (172.7) (38.1) (383.0)Proceeds received from exercise of stock options – 5.3 2.6 50.8Shares repurchased to satisfy employee tax (0.1) (0.8) (5.0) (7.4)obligations for vested stock-based awardsNet cash used in financing activities (6.9) (197.1) (40.5) (327.3)Effect of currency rate changes on cash and cash 14.8 (1.6) 21.8 (7.3)equivalentsNet change in cash, cash equivalents and restricted 133.7 37.5 187.5 9.0cashCash, cash equivalents and restricted cash, beginning 318.5 259.2 264.7 287.7of periodCash, cash equivalents and restricted cash, end of $ 452.2 $ 296.7 $ 452.2 $ 296.7periodAvantor, Inc. and subsidiariesReconciliations of non-GAAP measuresAdjusted EBITDA and Adjusted EBITDA Margin(dollars in millions, % Threemonths ended June30, Sixmonths ended June30,based on net sales) 2025 2024 2025 2024 $ % $ % $ % $ %Net income $ 64.7 3.8% $ 92.9 5.5% $ 129.2 4.0% $ 153.3 4.5%Amortization 75.5 4.5% 74.9 4.4% 149.4 4.6% 150.2 4.4%Loss on extinguishment – -% 1.9 -% – -% 4.4 0.1%of debtRestructuring and 21.4 1.3% 9.7 0.6% 25.8 0.8% 32.9 1.0%severance charges1Transformation 20.4 1.2% 16.2 1.0% 35.8 1.1% 29.5 0.9%expenses2Reserve for certain legal 3.6 0.2% – -% 3.6 0.1% – -%matters, net3Other4 6.6 0.4% (0.3) -% 10.6 0.3% (0.8) -%Pension termination – -% – -% 18.1 0.6% – -%charges5Income tax benefit (31.0) (1.8)% (27.3) (1.6)% (56.1) (1.8)% (50.9) (1.5)%applicable to pretaxadjustmentsAdjusted net income 161.2 9.6% 168.0 9.9% 316.4 9.7% 318.6 9.4%Interest expense, net 43.4 2.6% 60.9 3.6% 85.6 2.6% 125.2 3.7%Depreciation 27.2 1.6% 27.7 1.5% 53.0 1.6% 52.0 1.6%Income tax provision 48.0 2.8% 49.0 2.9% 94.3 2.9% 92.8 2.7%applicable toAdjusted Net incomeAdjusted EBITDA $ 279.8 16.6% $ 305.6 17.9% $ 549.3 16.8% $ 588.6 17.4%â”â”â”â”â”â”â”â”â”1. Reflects the incremental expenses incurred in the period related to restructuring initiatives to increase profitability and productivity. Costs included in this caption are specific to employee severance, site-related exit costs, and contract termination costs. These expenses represent costs incurred to achieve the Company's publicly-announced cost transformation initiative.2. Represents incremental expenses directly associated with the Company's publicly-announced cost transformation initiative, primarily related to the cost of external advisors.3. Represents charges and legal costs, net of recoveries, in connection with certain litigation and other contingencies that are unrelated to our core operations and not reflective of on-going business and operating results.4. Represents net foreign currency (gain) loss from financing activities, other stock-based compensation expense (benefit) and a purchase price adjustment related to the sale of our Clinical Services business in 2024.5. Represents pension termination charges related to termination of our U.S. Pension Plan.Avantor, Inc. and subsidiariesReconciliations of non-GAAP measures (continued)Adjusted Operating Income and Adjusted Operating Income Margin(dollars in millions, %based on Threemonths ended June30, Sixmonths ended June30,net sales) 2025 2024 2025 2024 $ % $ % $ % $ %Net income $ 64.7 3.8% $ 92.9 5.5% $ 129.2 4.0% $ 153.3 4.5%Interest expense, net 43.4 2.6% 60.9 3.6% 85.6 2.6% 125.2 3.7%Income tax expense 17.0 1.0% 21.7 1.3% 38.2 1.1% 41.9 1.2%Loss on extinguishment – -% 1.9 -% – -% 4.4 0.1%of debtOther (expense) income, net 3.7 0.3% (1.6) (0.1)% 23.2 0.8% (2.7) -%Operating income 128.8 7.7% 175.8 10.3% 276.2 8.5% 322.1 9.5%Amortization 75.5 4.5% 74.9 4.4% 149.4 4.6% 150.2 4.4%Restructuring and severance 21.4 1.3% 9.7 0.6% 25.8 0.8% 32.9 1.0%charges1Transformation expenses2 20.4 1.2% 16.2 1.0% 35.8 1.1% 29.5 0.9%Reserve for certain legal 3.6 0.2% – -% 3.6 0.1% – -%matters, net3Other4 2.5 0.1% 0.6 -% 4.2 0.1% 0.9 -%Adjusted Operating Income $ 252.2 15.0% $ 277.2 16.3% $ 495.0 15.2% $ 535.6 15.8%â”â”â”â”â”â”â”â”â”1. Reflects the incremental expenses incurred in the period related to restructuring initiatives to increase profitability and productivity. Costs included in this caption are specific to employee severance, site-related exit costs, and contract termination costs. These expenses represent costs incurred to achieve the Company's publicly-announced cost transformation initiative.2. Represents incremental expenses directly associated with the Company's publicly-announced cost transformation initiative, primarily related to the cost of external advisors.3. Represents charges and legal costs, net of recoveries, in connection with certain litigation and other contingencies that are unrelated to our core operations and not reflective of on-going business and operating results.4. Represents other stock-based compensation expense (benefit) and a purchase price adjustment related to the sale of our Clinical Services business in 2024.Avantor, Inc. and subsidiariesReconciliations of non-GAAP measures (continued)Adjusted earnings per share(shares in millions) Threemonths ended Sixmonths ended June30, June30, 2025 2024 2025 2024Diluted earnings per share (GAAP) $ 0.09 $ 0.14 $ 0.19 $ 0.22Dilutive impact of convertible instruments – – – -Fully diluted earnings per share (non-GAAP) 0.09 0.14 0.19 0.22Amortization 0.11 0.11 0.22 0.22Loss on extinguishment of debt – – – 0.01Restructuring and severance charges 0.03 0.02 0.04 0.05Transformation expenses 0.03 0.02 0.04 0.04Reserve for certain legal matters, net 0.01 – 0.01 -Other 0.02 – 0.01 -Pension termination charges – – 0.03 -Income tax benefit applicable to pretax adjustments (0.05) (0.04) (0.08) (0.07)Adjusted EPS (non-GAAP) $ 0.24 $ 0.25 $ 0.46 $ 0.47Weighted average diluted shares outstanding:Share count for Adjusted EPS (non-GAAP) 681.8 682.6 682.0 681.9Free cash flow(in millions) Threemonths ended Sixmonths ended June30, June30, 2025 2024 2025 2024Net cash provided by operating activities $ 154.4 $ 281.1 $ 263.7 $ 422.7Capital expenditures (29.6) (45.8) (57.6) (80.5)Divestiture-related transaction expenses and taxes 0.6 – 1.4 -paidFree cash flow (non-GAAP) $ 125.4 $ 235.3 $ 207.5 $ 342.2Adjusted net leverage(dollars in millions) June 30, 2025Total debt, gross $ 4,261.0Less cash and cash equivalents (449.4) $ 3,811.6Trailing twelve months Adjusted EBITDA(1) $ 1,141.8Trailing twelve months ongoing stock-based compensation expense 51.8 $ 1,193.6Adjusted net leverage (non-GAAP) 3.2 x1. Represents the Adjusted EBITDA ofAvantor for the trailing twelve-month period minus the results attributable to the divested business as if such divestiture had been completed on the first day of such trailing twelve-month period, as contemplated by our debt covenants.Avantor, Inc. and subsidiariesReconciliations of non-GAAP measures (continued)Net sales by segment(in millions) June30, Reconciliation of net sales growth (decline) to organic net sales growth (decline) Net sales Foreign Divestiture Organic growth currency impact net sales (decline) impact growth (decline) 2025 2024 $ $ $ $ $ $Three months ended:Laboratory Solutions $ 1,122.1 $ 1,155.7 $ (33.6) $ 25.6 $ (48.1) $ (11.1)Bioscience Production 561.3 547.1 14.2 5.8 – 8.4Total $ 1,683.4 $ 1,702.8 $ (19.4) $ 31.4 $ (48.1) $ (2.7)Six months ended:Laboratory Solutions $ 2,187.1 $ 2,312.8 $ (125.7) $ 11.1 $ (92.2) $ (44.6)Bioscience Production 1,077.7 1,069.8 7.9 1.3 – 6.6Total $ 3,264.8 $ 3,382.6 $ (117.8) $ 12.4 $ (92.2) $ (38.0)(dollars in millions, % based June30, Reconciliation of net sales growth (decline) toon net sales) organic net sales growth (decline) Net sales Foreign Divestiture Organic growth currency impact net sales (decline) impact growth (decline) 2025 2024 $ $ % % % %Three months ended:Laboratory Solutions $ 1,122.1 $ 1,155.7 (2.9)% 2.3% (4.2)% (1.0)%Bioscience Production 561.3 547.1 2.6% 1.1% -% 1.5%Total $ 1,683.4 $ 1,702.8 (1.1)% 1.9% (2.8)% (0.2)%Six months ended:Laboratory Solutions $ 2,187.1 $ 2,312.8 (5.4)% 0.5% (4.0)% (1.9)%Bioscience Production 1,077.7 1,069.8 0.7% 0.1% -% 0.6%Total $ 3,264.8 $ 3,382.6 (3.5)% 0.3% (2.7)% (1.1)%Adjusted Operating Income by segment(dollars in millions, % Threemonths ended June30, Sixmonths ended June30,represent AdjustedOperating Income margin) 2025 2024 2025 2024 $ % $ % $ % $ %Laboratory Solutions $ 133.3 11.9% $ 150.9 13.1% $ 272.3 12.5% $ 299.1 12.9%Bioscience Production 139.7 24.9% 144.0 26.3% 263.1 24.4% 270.9 25.3%Corporate (20.8) -% (17.7) -% (40.4) -% (34.4) -%Total $ 252.2 15.0% $ 277.2 16.3% $ 495.0 15.2% $ 535.6 15.8%

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