Alkermes plc (Nasdaq: ALKS):
IRISH TAKEOVER PANEL
OPENING POSITION DISCLOSURE UNDER RULE 8.1(a) AND (b) OF THE IRISH TAKEOVER PANEL ACT, 1997, TAKEOVER RULES, 2022 BY AN OFFEROR OR AN OFFEREE
1.KEY INFORMATION
(a) Full name of discloser: Alkermes plc(b) Owner or controller of interests and short N/A positions disclosed, if different from 1(a): The naming of nominee or vehicle companies is insufficient. For a trust, the trustee(s), settlor and beneficiaries must be named.(c) Name ofofferor/offeree in relation to whose Avadel relevant securities this form relates: Pharmaceuticals Use a separate form for eachofferor/offeree plc(d) Is the discloser theofferor or the offeree? OFFEROR(e) Date position held: 3 November The latest practicable date prior to the 2025 disclosure(f) In addition to the company in 1(c) above, is N/A the discloser also making disclosures in respect of any other party to the offer? If it is a cash offer or possible cash offer, state “N/A”
2.INTERESTS AND SHORT POSITIONS
If there are interests and positions to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2 for each additional class of relevant security.
Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure relates (Note 1)
N/A
All interests and all short positions should be disclosed.
Details of options including rights to subscribe for new securities and any open stock-settled derivative positions (including traded options), or agreements to purchase or sell relevant securities, should be given on a Supplemental Form8.
3.INTERESTS AND SHORT POSITIONS OF PERSONS ACTING IN CONCERT WITH THE PARTY MAKING THE DISCLOSURE
Details of any interests and short positions (including directors'and other employee options) of any person acting in concert withthe party making the disclosure:Interests of J.P. Morgan (together with its members of staff under Rule3.3(b)(v) of Part A of the Irish Takeover Rules), financial advisors toAlkermes plc, but, for clarity, not held on behalf of Alkermes plc: Party Class of Number of Percentage Relevant ordinary of total Security shares held issued share at midnight capital (ET) on (rounded) 3 November 2025 55I, LLC Ordinary 53 0.0001% shares of US$0.01 each JPMorgan Ordinary 13,500 0.0139% Chase Bank, shares of National US$0.01 Association each TOTAL 13,553 0.0139%Details of any open stock-settled derivative positions (including tradedoptions), or agreements to purchase or sell relevant securities, shouldbegiven on a Supplemental Form 8.
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4. OTHER INFORMATION
(a) Indemnity and other dealing arrangements
Details of any indemnity or option arrangement, or any agreementor understanding, formal or informal, relating to relevant securitieswhich may be an inducement to deal or refrain from dealing enteredinto by the party to the offer making the disclosure or any personacting in concert with it:Irrevocable commitments and letters of intent should not be included. Ifthere are no such agreements, arrangements or understandings, state”none”None
(b) Agreements, arrangements or understandings relating to options or derivatives
Full details of any agreement, arrangement or understandingbetween the person disclosing and any other person relating to thevoting rights of any relevant securities under any option referredto on this form or relating to the voting rights or future acquisitionor disposal of any relevant securities to which any derivativereferred to on this form is referenced. If none, this should be stated.None
(c) Attachments
Is a Supplemental Form 8 attached? YES/NO NoDate of disclosure: 5 November 2025Contact name: Sandy Coombs, AlkermesTelephone number: +1 781 609 6377Public disclosures under Rule 8.1 of the Rules must be made to aRegulatory Information Service.
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NOTES ON FORM 8.1(a) and (b)
— See the definition of “interest in a relevant security” in Rule 2.5 of Part A of the Rules and see Rule 8.6(a) of Part B of the Rules.
— See the definition of “relevant securities” in Rule 2.1 of Part A of the Rules.
— If details included in a disclosure under Rule 8 are incorrect, they should be corrected as soon as practicable in a subsequent disclosure. Such disclosure should state clearly that it corrects details disclosed previously, identify the disclosure or disclosures being corrected, and provide sufficient detail for the reader to understand the nature of the corrections. In the case of any doubt, the Panel should be consulted.
For full details of disclosure requirements, see Rule 8 of the Rules. If in doubt, consult the Panel.
References in these notes to “the Rules” are to the Irish Takeover Panel Act, 1997, Takeover Rules, 2022.
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SOURCE Alkermes plc
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